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The Kinase DYRK1A Reciprocally Regulates the Differentiation of Th17 and Regulatory T Cells

May 22, 2015 Amy Clugston

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Video Presentation

  • 2:05 - Healthy immune response balances pro- and anti-inflammatory forces, too much inflammation leads to autoimmunity and not enough inflammation leads to infection and predispose to cancer.

  • 24:18 - DYRK1A Inhibition Enhances Treg and inhibits Th17 differenctiation

In DYRK1A Gene Research Tags Present Day - 2015
← Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1aDyrk1A Phosphorylates Parkin at Ser-131 and Negatively Regulates its Ubiquitin E3 Ligase Activity. →

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